We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn about our cookie policy.
Cayman (Z)-Ligustilide
List Price
$602.00
Your Price
$602.00
Cayman (Z)-Ligustilide - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-26908-100
MFG.PART:
26908-100
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
(Z)-Ligustilide is a phthalide that has been found in A. graveolens and T. montana roots and has diverse biological activities.,,, It inhibits autophagy and restores Nurr77 expression and sensitivity to tamoxifen (Item No. ) in tamoxifen-resistant MCF-7 cells. (Z)-Ligustilide (8-32 mg/kg) increases cerebral expression of Nrf2 and HO-1 and reduces infarct volume and neuronal loss in a rat model of cerebral ischemia and reperfusion injury. It decreases mechanical and thermal hyperalgesia in a rat model of inflammatory pain induced by complete Freunds adjuvant (CFA). (Z)-Ligustilide restores gait coordination, reduces spinal cord inducible nitric oxide synthase (iNOS) expression, and inhibits production of prostaglandin E2 (PGE2; Item No. ), TNF-α, and IL-1β in a rat model of spinal cord injury.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
3Z-
CAS Number
81944-09-4
Synonyms
- cis-Ligustilide
- Ligustilide A
Molecular Formula
C12H14O2
Formula Weight
190.2
Purity
≥95%
Formulation
A neat oil
Solubility
- DMF: 1 mg/mL
- DMSO: 1 mg/mL
- Ethanol: Miscible
λmax
285, 322 nm
SMILES
O=C1O/C(C2=C1C=CCC2)=C\CCC
InChi Code
InChI=1S/C12H14O2/c1-2-3-8-11-9-6-4-5-7-10(9)12(13)14-11/h5,7-8H,2-4,6H2,1H3/b11-8-
InChi Key
IQVQXVFMNOFTMU-FLIBITNWSA-N
Origin
Plant/Angelica sinensis
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-26908-100 |
|---|---|
| Supplier Part Number | 26908-100 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 81944-09-4 |
| Energy Star | No |
| Green | No |
| Controlled | N |