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Cayman (Z)-Ligustilide
List Price
$169.00
Your Price
$169.00
Cayman (Z)-Ligustilide - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-26908-25
MFG.PART:
26908-25
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
(Z)-Ligustilide is a phthalide that has been found in A. graveolens and T. montana roots and has diverse biological activities.1,2,3,4 It inhibits autophagy and restores Nurr77 expression and sensitivity to tamoxifen (Item No. 13258) in tamoxifen-resistant MCF-7 cells.2 (Z)-Ligustilide (8-32 mg/kg) increases cerebral expression of Nrf2 and HO-1 and reduces infarct volume and neuronal loss in a rat model of cerebral ischemia and reperfusion injury.5 It decreases mechanical and thermal hyperalgesia in a rat model of inflammatory pain induced by complete Freunds adjuvant (CFA).3 (Z)-Ligustilide restores gait coordination, reduces spinal cord inducible nitric oxide synthase (iNOS) expression, and inhibits production of prostaglandin E2 (PGE2; Item No. 14010), TNF-α, and IL-1β in a rat model of spinal cord injury.4
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
3Z-
CAS Number
81944-09-4
Synonyms
- cis-Ligustilide
- Ligustilide A
Molecular Formula
C12H14O2
Formula Weight
190.2
Purity
≥95%
Formulation(Request formulation change)
A neat oil
Solubility(Learn about Variance in Solubility)
- DMF: 1 mg/mL
- DMSO: 1 mg/mL
- Ethanol: Miscible
λmax
285, 322 nm
SMILES
O=C1O/C(C2=C1C=CCC2)=C\CCC
InChi Code
InChI=1S/C12H14O2/c1-2-3-8-11-9-6-4-5-7-10(9)12(13)14-11/h5,7-8H,2-4,6H2,1H3/b11-8-
InChi Key
IQVQXVFMNOFTMU-FLIBITNWSA-N
Origin
Plant/Angelica sinensis
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-26908-25 |
|---|---|
| Supplier Part Number | 26908-25 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 81944-09-4 |
| Energy Star | No |
| Green | No |
| Controlled | N |