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Cayman 3,4-Methylenedioxy-?-Ethylmethylaminohexanophenone (Hydroc
List Price
$278.00
Your Price
$278.00
Cayman 3,4-Methylenedioxy-?-Ethylmethylaminohexanophenone (Hydrochloride), 1-(Benzo[D][1,3]Dioxol-5-Yl)-2-(Ethyl(Methyl)Amino)Hexan-1-One, Monohydrochloride, 5 Mg - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-27077-5
MFG.PART:
27077-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
GAT228 is an allosteric agonist of cannabinoid receptor 1 (CB1), the R-(+)-enantiomer of the CB1 positive allosteric modulator (PAM) GAT229 (Item No. ), and a component of the racemic mixture GAT211, which acts as both an agonist and PAM., GAT228 increases β-arrestin recruitment, cAMP inhibition, and ERK1/2 and PLCβ3 phosphorylation in HEK293A cells expressing GFP-tagged human CB1 (hCB1-GFP) in a concentration-dependent manner. Unlike GAT229, GAT228 has no effect on the binding of the CB receptor agonist CP 55,940 to membranes from CHO cells expressing hCB1 when used at concentrations up to 1 µM. It inhibits excitatory postsynaptic currents (EPSCs) in a subset of CB1-expressing murine autaptic hippocampal neurons when used at a concentration of 1 µM.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
3-[(1R)-2-
CAS Number
1446648-15-2
Molecular Formula
C22H18N2O2
Formula Weight
342.4
Purity
≥98%
Formulation
A solid
Solubility
- DMSO: 20 mg/ml
SMILES
O=[N+](C[C@H](C1=CC=CC=C1)C2=C(C3=CC=CC=C3)NC4=CC=CC=C42)[O-]
InChi Code
InChI=1S/C22H18N2O2/c25-24(26)15-19(16-9-3-1-4-10-16)21-18-13-7-8-14-20(18)23-22(21)17-11-5-2-6-12-17/h1-14,19,23H,15H2/t19-/m1/s1
InChi Key
OHZDCJJHWPHZJD-LJQANCHMSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-27077-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 27077-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |