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Cayman N-desmethyl Bendamustine
List Price $422.00 Your Price $422.00
Cayman N-desmethyl Bendamustine - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-27171-1
MFG.PART: 27171-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
N-desmethyl Bendamustine is an active metabolite of the DNA alkylating agent bendamustine (Item No. ). N-desmethyl Bendamustine is formed through demethylation of the benzimidazole ring in bendamustine by the cytochrome P450 (CYP) isoform CYP1A2. It inhibits proliferation of non-cancerous peripheral blood leukocytes (PBLs; IC50 = 45 µM) and SU-DHL-1, SU-DHL-9, and Daudi lymphoma cells (IC50s = 270, 170, and 120 µM, respectively).
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
6-[bis(2-
CAS Number
41515-13-3
Synonyms
- nor-Bendamustine
Molecular Formula
C15H19Cl2N3O2
Formula Weight
344.2
Purity
≥95%
Formulation
A solid
Solubility
- Acetonitrile:Methanol (1:1): soluble
- DMSO: soluble
SMILES
ClCCN(CCCl)C1=CC=C(N=C(CCCC(O)=O)N2)C2=C1
InChi Code
InChI=1S/C15H19Cl2N3O2/c16-6-8-20(9-7-17)11-4-5-12-13(10-11)19-14(18-12)2-1-3-15(21)22/h4-5,10H,1-3,6-9H2,(H,18,19)(H,21,22)
InChi Key
BPZIKXXNXMYQPN-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-27171-1 |
|---|---|
| Supplier Part Number | 27171-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | Canada |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 41515-13-3 |
| Energy Star | No |
| Green | No |
| Controlled | N |