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Cayman Ganglioside GM2 (bovine brain) (sodium salt)
List Price
$321.00
Your Price
$321.00
Cayman Ganglioside GM2 (bovine brain) (sodium salt) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-27192-500
MFG.PART:
27192-500
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Ganglioside gM2 is a glycosphingolipid component of cellular membranes, primarily the plasma membrane. Gangliosides isolated from apoptogenic glioblastoma multiforme (GBM) cells are enriched in ganglioside gM2 compared with nonapoptogenic GBM cells, and ganglioside gM2 induces activated T cell death when used at a concentration of 150 μg/mL in vitro. Serum ganglioside gM2 levels are increased in patients with breast cancer or cholangiocarcinoma., Levels of ganglioside gM2 are elevated in the brain of patients with Sandhoff disease, as well as feline and mouse models of the disease. Ganglioside gM2 accumulates in the lysosomes of individuals with Tay-Sachs disease and gM2-activator deficiency, as well as in the CNS of patients with and animal models of mucopolysaccharide storage disorders and Niemann-Pick disease types A, C1, and C2., This product contains ganglioside gM2 molecular species with primarily C18:0 fatty acyl chain lengths. As this product is derived from a natural source, there may be variations in the sphingoid backbone.
WARNING This product is not for human or veterinary use.
Technical Information
CAS Number
19600-01-2
Synonyms
- gM2
- Monosialoganglioside gM2
Molecular Formula
C67H120N3O26 • Na (for stearoyl)
Formula Weight
1383.7
Purity
≥98%
Formulation
A solid
Solubility
- Chloroform:Methanol (2:1): soluble
- Water: soluble
SMILES
OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@@]2([H])[C@@H]([C@@]([C@H]([C@H](O2)CO)O[C@]3([H])O[C@@H]([C@@H]([C@@H]([C@H]3NC(C)=O)O)O)CO)([H])O[C@]4(C([O-])=O)C[C@H](O)[C@@H](NC(C)=O)[C@@]([C@@H]([C@H](O)CO)O)([H])O4)O)O[C@H]1OC[C@@H]([C@H](O)/C=C/CCCCCCCCCCCCC)NC(CCCCCCCCCCCCCCCCC)=O.[Na+]
InChi Code
InChI=1S/C67H121N3O26.Na/c1-5-7-9-11-13-15-17-19-20-22-24-26-28-30-32-34-50(80)70-43(44(77)33-31-29-27-25-23-21-18-16-14-12-10-8-6-2)40-89-64-57(85)56(84)59(48(38-73)91-64)93-65-58(86)62(60(49(39-74)92-65)94-63-52(69-42(4)76)55(83)54(82)47(37-72)90-63)96-67(66(87)88)35-45(78)51(68-41(3)75)61(95-67)53(81)46(79)36-71;/h31,33,43-49,51-65,71-74,77-79,81-86H,5-30,32,34-40H2,1-4H3,(H,68,75)(H,69,76)(H,70,80)(H,87,88);/q;+1/p-1/b33-31+;/t43-,44+,45-,46+,47+,48+,49+,51+,52+,53+,54-,55+,56+,57+,58+,59+,60-,61+,62+,63-,64+,65-,67-;/m0./s1
InChi Key
YZCIBJIDUSQSAE-VUDKKWOPSA-M
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-27192-500 |
|---|---|
| Supplier Part Number | 27192-500 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | Switzerland |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 19600-01-2 |
| Energy Star | No |
| Green | No |
| Controlled | N |