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Cayman N-methyl Mesoporphyrin IX
List Price $103.00 Your Price $103.00
Cayman N-methyl Mesoporphyrin IX - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-27210-1
MFG.PART: 27210-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
N-methyl Mesoporphyrin IX is a transition state analog of porphyrin and an inhibitor of ferrochelatase. It inhibits ferrochelatase in mouse liver mitochondria in vitro and in vivo, leading to an accumulation of porphyrin in isolated liver mitochondria following administration of an intravenous dose of 80 nmol. N-methyl Mesoporphyrin IX has been used as a turn-on biosensor for target DNA sequences when used in complex with a g-quadruplex-forming sequence fused to a DNA sequence complementary to the target sequence. It has also been used to detect amyloid-β (1-40) (Aβ40) fibrils in vitro and in live PC12 cells overexpressing Aβ. N-methyl Mesoporphyrin displays excitation/emission maxima of 399/610 nm, respectively.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
8,13-diethyl-
CAS Number
142234-85-3
Molecular Formula
C35H40N4O4
Formula Weight
580.7
Purity
≥95% (mixture of isomers)
Emission
610 nm
Excitation
399 nm
Formulation
A crystalline solid
Solubility
- DMF: 20 mg/mL
- DMF:PBS (pH 7.2) (1:5): 0.17 mg/mL
- DMSO: 15 mg/mL
λmax
299, 395, 564 nm
SMILES
CC1=C2[NH]C(/C=C(C(CCC(O)=O)=C3C)\[N]=C3/C=C4[N](C)/C(C(C)=C\4CC)=C\C5=[N]/C(C(C)=C5CC)=C\2)=C1CCC(O)=O
InChi Code
InChI=1S/C35H40N4O4/c1-8-22-18(3)26-14-27-19(4)24(10-12-34(40)41)29(36-27)15-30-25(11-13-35(42)43)20(5)28(38-30)16-33-23(9-2)21(6)32(39(33)7)17-31(22)37-26/h14-17,36H,8-13H2,1-7H3,(H,40,41)(H,42,43)/b26-14-,27-14-,28-16-,29-15-,30-15-,31-17-,32-17-,33-16-
InChi Key
XASXJWXLPCEQJN-UQOLDQHFSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-27210-1 |
|---|---|
| Supplier Part Number | 27210-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 142234-85-3 |
| Energy Star | No |
| Green | No |
| Controlled | N |