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Cayman AC-AAVALLPAVLLALLAP-IETD-CHO (trifluoroacetate salt)
List Price $112.00 Your Price $112.00
Cayman AC-AAVALLPAVLLALLAP-IETD-CHO (trifluoroacetate salt) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-27438-500
MFG.PART: 27438-500
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
AC-AAVALLPAVLLALLAP-IETD-CHO is a composite of AC-IETD-CHO (Item No. 27100), a peptide inhibitor of caspase-8, and a cell-permeable hydrophobic sequence derived from K-FGF.1,2 It is an inhibitor of both caspase-8 and granzyme B.1,3,4 It prevents death of SKOV3 ovarian carcinoma cells transfected with Survivin and granzyme B-induced apoptosis (SAGA) when used at a concentration of 20 µM.4
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-acetyl-L-
Synonyms
- AC-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Ile-Glu-Thr-Asp-CHO
- Caspase-8 Inhibitor I
Molecular Formula
C95H162N20O26 • XCF3COOH
Formula Weight
2000.4
Purity
≥95%
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- Formic Acid: 1 mg/mL
SMILES
CC(C)[C@@H](C(N[C@@H](C)C(N[C@H](C(N[C@H](C(N1CCC[C@H]1C(N[C@@H](C)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](C)C(N[C@H](C(N[C@H](C(N[C@@H](C)C(N2CCC[C@H]2C(N[C@]([H])(C(N[C@H](C(N[C@]([H])(C(N[C@@H](CC(O)=O)C=O)=O)[C@H](O)C)=O)CCC(O)=O)=O)[C@@H](C)CC)=O)=O)=O)CC(C)C)=O)CC(C)C)=O)=O)CC(C)C)=O)CC(C)C)=O)C(C)C)=O)=O)=O)CC(C)C)=O)CC(C)C)=O)=O)NC([C@H](C)NC([C@H](C)NC(C)=O)=O)=O.FC(F)(C(O)=O)F
InChi Code
InChI=1S/C95H162N20O26.C2HF3O2/c1-27-52(18)75(92(138)103-62(32-33-71(119)120)82(128)113-76(59(25)117)93(139)102-61(43-116)42-72(121)122)112-89(135)70-31-28-34-114(70)94(140)58(24)101-84(130)64(37-45(4)5)107-85(131)65(38-46(6)7)104-78(124)54(20)98-83(129)63(36-44(2)3)106-86(132)67(40-48(10)11)108-91(137)74(51(16)17)111-81(127)57(23)99-88(134)69-30-29-35-115(69)95(141)68(41-49(12)13)109-87(133)66(39-47(8)9)105-79(125)55(21)100-90(136)73(50(14)15)110-80(126)56(22)97-77(123)53(19)96-60(26)118;3-2(4,5)1(6)7/h43-59,61-70,73-76,117H,27-42H2,1-26H3,(H,96,118)(H,97,123)(H,98,129)(H,99,134)(H,100,136)(H,101,130)(H,102,139)(H,103,138)(H,104,124)(H,105,125)(H,106,132)(H,107,131)(H,108,137)(H,109,133)(H,110,126)(H,111,127)(H,112,135)(H,113,128)(H,119,120)(H,121,122);(H,6,7)/t52-,53-,54-,55-,56-,57-,58-,59+,61-,62-,63-,64-,65-,66-,67-,68-,69-,70-,73-,74-,75-,76-;/m0./s1
InChi Key
COGMWHXRSXGJMX-PWAYNZGCSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-27438-500 |
|---|---|
| Supplier Part Number | 27438-500 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| Controlled | N |