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Cayman Hexanoic Acid-D11; Purity- Greater Than Or Equal To 99% De
List Price
$37.00
Your Price
$37.00
Cayman Hexanoic Acid-D11; Purity- Greater Than Or Equal To 99% Deuterated Forms (D1-D11); Size- 100 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-28082-100
MFG.PART:
28082-100
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Lysosphingomyelin is an endogenous bioactive sphingolipid and a constituent of lipoproteins., It is produced by the removal of the acyl group from sphingomyelin by a deacylase and acts as a precursor in the biosynthesis of sphingosine-1-phosphate (S1P; Item No. ). D-erythro Lysosphingomyelin is an agonist of the S1P receptors S1P1, S1P2, and S1P3 (EC50s = 167.7, 368.1, and 482.6 nM, respectively, for the human receptors). It is also an agonist of the orphan receptor ovarian cancer G protein-coupled receptor 1 (ORG1) that induces calcium accumulation in cells overexpressing OGR1 (EC50 = ~35 nM). Levels of D-erythro lysosphingomyelin are increased in skin isolated from patients with atopic dermatitis, as well as postmortem brain from patients with Niemann-Pick disease type A, but not type B., L-threo lysosphingomyelin is also an S1P1-3 agonist (EC50s = 19.3, 131.8, and 313.3 nM, respectively). This product is a mixture of D-erythro and L-threo lysosphingomyelin. As this product is derived from a natural source, there may be variations in the sphingoid backbone. [Matreya, LLC. Catalog No. 1321]
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2-[[[(2-amino-
CAS Number
82970-80-7
Synonyms
- D-erythro/L-threo Lyso SM(18:1)
- D-erythro/L-threo Sphingosine-1-Phosphocholine (d18:1)
- D-erythro/L-threo-Sphingosylphosphorylcholine
Molecular Formula
C23H49N2O5P
Formula Weight
464.6
Purity
≥98%
Formulation
A solid
Solubility
- Chloroform:Methanol (2:1): soluble
SMILES
NC(COP(OCC[N+](C)(C)C)([O-])=O)C(O)/C=C/CCCCCCCCCCCCC
InChi Code
InChI=1S/C23H49N2O5P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-23(26)22(24)21-30-31(27,28)29-20-19-25(2,3)4/h17-18,22-23,26H,5-16,19-21,24H2,1-4H3/b18-17+
InChi Key
JLVSPVFPBBFMBE-ISLYRVAYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-28082-100 |
|---|---|
| Featured | No |
| Supplier Part Number | 28082-100 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | Canada |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | Y |
| CAS Number | 95348-44-0 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |