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Cayman Histone H3K27Me3 (23-34) (human, mouse, rat, bovine) (trifluoroacetate salt)
List Price $307.00 Your Price $307.00
Cayman Histone H3K27Me3 (23-34) (human, mouse, rat, bovine) (trifluoroacetate salt) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-28143-1
MFG.PART: 28143-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Histone H3K27Me3 (23-34) is a peptide fragment of histone H3 that corresponds to amino acid residues 24-35 of the human histone H3.1 and H3.2 sequences. Trimethylation of histone H3 at lysine 27 is associated with gene silencing. It is involved in tumor progression through its regulation by enhancer of zeste homolog 2 (EZH2) and transcriptional repression of tumor suppressor genes., Levels of H3K27Me3 are reduced in 293 T-REx cells containing EEDR236T and SUZ12G610V mutations and in lymphoblastoid cells isolated from patients with Weaver syndrome, a rare overgrowth disorder characterized by EZH2, EED, or SUZ12 mutations, cancer susceptibility, and various distinctive physical features. Histone H3K27Me3 (23-34) has been used in AlphaLISA® assays to verify antibody specificity.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
L-lysyl-L-
Synonyms
- [Lys(Me3)27]-Histone H3 (23-34)
- Histone H3 (23-34) (Lys27me3)
- KAAR-K(Me3)-SAPATGG
Molecular Formula
C49H89N17O15 • XCF3COOH
Formula Weight
1156.3
Purity
≥95%
Formulation
A solid
Solubility
- Water: 1 mg/mL
SMILES
C[N+](CCCC[C@H](NC([C@@H](NC([C@H](C)NC([C@H](C)NC([C@@H](N)CCCCN)=O)=O)=O)CCCNC(N)=N)=O)C(N[C@H](C(N[C@@H](C)C(N1CCC[C@H]1C(N[C@@H](C)C(N[C@]([H])(C(NCC(NCC([O-])=O)=O)=O)[C@H](O)C)=O)=O)=O)=O)CO)=O)(C)C.O=C(O)C(F)(F)F
InChi Code
InChI=1S/C49H89N17O15.C2HF3O2/c1-26(58-42(75)31(51)15-9-11-19-50)39(72)57-27(2)40(73)61-33(17-13-20-54-49(52)53)43(76)62-32(16-10-12-22-66(6,7)8)44(77)63-34(25-67)45(78)60-29(4)48(81)65-21-14-18-35(65)46(79)59-28(3)41(74)64-38(30(5)68)47(80)56-23-36(69)55-24-37(70)71;3-2(4,5)1(6)7/h26-35,38,67-68H,9-25,50-51H2,1-8H3,(H14-,52,53,54,55,56,57,58,59,60,61,62,63,64,69,70,71,72,73,74,75,76,77,78,79,80);(H,6,7)/t26-,27-,28-,29-,30+,31-,32-,33-,34-,35-,38-;/m0./s1
InChi Key
OQJIFAQOQASJCP-JNOZJHQNSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-28143-1 |
|---|---|
| Supplier Part Number | 28143-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| Controlled | N |