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Cayman Metoprolol-d6 (tartrate)
List Price $267.00 Your Price $267.00
Cayman Metoprolol-d6 (tartrate) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-28188-1
MFG.PART: 28188-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Metoprolol-d6 is intended for use as an internal standard for the quantification of metoprolol (Item No. ) by GC- or LC-MS. Metoprolol is a β1-adrenergic receptor (β1-AR) antagonist (Ki = 47 nM in CHO Cells expressing the human receptor). It is selective for β1- over β2- and β3-ARs (Kis = 2,730 and >10,000 nM, respectively, in CHO Cells expressing the human receptors). Metoprolol (4.7 µM) reduces GTP-induced adenylyl cyclase (AC) activity in CHO Cells expressing β1- and β2-ARs. It reduces pulse rate in isolated rat atria in a concentration-dependent manner. Metoprolol (10 mg/kg) reduces increased heart rate and mean arterial pressure (MAP) in a rat model of systolic hypertension induced by a fructose-rich diet. Formulations containing metoprolol have been used in the treatment of exercised-induced hypertension, angina, and tachycardia.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
1-[4-(2-
Molecular Formula
C15H19D6NO3 • 1/2C4H6O6
Formula Weight
348.5
Purity
≥99% deuterated forms (d1-d6)
Formulation
A solid
Solubility
- DMSO: soluble
- Methanol: soluble
- Water: soluble
SMILES
COCCC1=CC=C(OCC(O)CNC(C([2H])([2H])[2H])C([2H])([2H])[2H])C=C1.OC([C@H](O)[C@@H](O)C(O)=O)=O.COCCC2=CC=C(OCC(O)CNC(C([2H])([2H])[2H])C([2H])([2H])[2H])C=C2
InChi Code
InChI=1S/2C15H25NO3.C4H6O6/c2*1-12(2)16-10-14(17)11-19-15-6-4-13(5-7-15)8-9-18-3;5-1(3(7)8)2(6)4(9)10/h2*4-7,12,14,16-17H,8-11H2,1-3H3;1-2,5-6H,(H,7,8)(H,9,10)/t;;1-,2-/M..1/s1/i2*1D3,2D3;
InChi Key
YGULWPYYGQCFMP-MFXGARSWSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-28188-1 |
|---|---|
| Supplier Part Number | 28188-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| Controlled | N |