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Cayman Crotonoside
List Price $101.00 Your Price $101.00
Cayman Crotonoside - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-28219-10
MFG.PART: 28219-10
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Crotonoside is a guanosine analog originally isolated from C. tiglium that has diverse biological activities.1,2,3 It is cytotoxic to P338, L5178Y, Sp2/O, HL-60, and Raji cells in vitro (EC50s = 21, 370, 120, 70, and 400 μM, respectively).1 Crotonoside (48 mg/kg per day for 12 days) reduces tumor growth by 60% in S-180 sarcoma and Ehrlich carcinoma solid tumor mouse models. It has been used as an internal standard for the semi-quantitative analysis and comparison of RNA metabolites in MCF-7 breast cancer cells and MCF-10A mammary epithelial cells.4 Crotonoside decreases the force and rate of contraction in isolated guinea pig atria (EC50s = 2.8 and 17.8 μM, respectively) and reduces carotid blood pressure in anesthetized cats when administered intravenously at a dose of 0.5 μmol/kg.2,3
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2,3-dihydro-
CAS Number
1818-71-9
Synonyms
- 2-Hydroxyadenosine
- Isoguanine riboside
- Isoguanosine
- NSC 12161
Molecular Formula
C10H13N5O5
Formula Weight
283.2
Purity
≥95%
Formulation(Request formulation change)
A crystalline solid
λmax
249, 300 nm
SMILES
OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C=NC(C2=N3)=C(N)NC3=O)O1
InChi Code
InChI=1S/C10H13N5O5/c11-7-4-8(14-10(19)13-7)15(2-12-4)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)/t3-,5-,6-,9-/m1/s1
InChi Key
MIKUYHXYGGJMLM-UUOKFMHZSA-N
Origin
Synthetic
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-28219-10 |
|---|---|
| Supplier Part Number | 28219-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1818-71-9 |
| Energy Star | No |
| Green | No |
| Controlled | N |