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Cayman Kevetrin (hydrochloride)
List Price $69.00 Your Price $69.00
Cayman Kevetrin (hydrochloride) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-28288-5
MFG.PART: 28288-5
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Kevetrin is an activator of p53.1,2 It increases levels of activated p53 and expression of p21 in A549 cells and decreases expression of the transcription factor E2F1 in a variety of cell lines.1,2 Kevetrin decreases cell viability in a panel of cancer cell lines with a mean IC50 value of 0.49 μM.3 It reduces tumor growth in MDA-MB-231, HT-29, PC3, HCT15, A549, NCI-H1975, CRL-1619, LNCaP, MIA PaCa, and SCC-5 mouse xenograft models when administered at a dose of 200 mg/kg.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
carbamimi
CAS Number
66592-89-0
Synonyms
- 4-Isothioureidobutyronitrile
- NSC 525990
Molecular Formula
C5H9N3S • HCl
Formula Weight
179.7
Purity
≥95%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- PBS (pH 7.2): 10 mg/mL
SMILES
NC(SCCCC#N)=N.Cl
InChi Code
InChI=1S/C5H9N3S.ClH/c6-3-1-2-4-9-5(7)8;/h1-2,4H2,(H3,7,8);1H
InChi Key
NCXJZJFDQMKRKM-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-28288-5 |
|---|---|
| Supplier Part Number | 28288-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 66592-89-0 |
| Energy Star | No |
| Green | No |
| Controlled | N |