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Cayman STING18
List Price
$94.00
Your Price
$94.00
Cayman STING18 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-28319-1
MFG.PART:
28319-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
STING18 is a competitive ligand of stimulator of interferon genes (STING; IC50 = 0.068 µM in a radioligand binding assay). It inhibits cGAMP-induced IFN-β production (IC50 = 11 µM) but does not stimulate IFN-β production (EC50 = >30 µM) in THP-1 cells.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2-[3-chloro- 4-(1,1-di methylethyl) phenyl]-3-(2, 3-dihydro- 1,4-benzo dioxin-6-yl)- 7-fluoro-1,2, 3,4-tetra hydro-1-oxo- 4-isoquino lineacetic acid
CAS Number
2706536-26-5
Synonyms
- Stimulator of Interferon Genes 18
Molecular Formula
C29H27ClFNO5
Formula Weight
524.0
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 10 mg/mL
- DMF:PBS (pH 7.2) (1:8): 0.11 mg/mL
- DMSO: 5 mg/mL
SMILES
FC1=CC=C2C(C(N(C3=CC(Cl)=C(C(C)(C)C)C=C3)C(C4=CC(OCCO5)=C5C=C4)C2CC(O)=O)=O)=C1
InChi Code
InChI=1S/C29H27ClFNO5/c1-29(2,3)22-8-6-18(14-23(22)30)32-27(16-4-9-24-25(12-16)37-11-10-36-24)20(15-26(33)34)19-7-5-17(31)13-21(19)28(32)35/h4-9,12-14,20,27H,10-11,15H2,1-3H3,(H,33,34)
InChi Key
JAIAHSWXASHNQH-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-28319-1 |
|---|---|
| Supplier Part Number | 28319-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 2706536-26-5 |
| Energy Star | No |
| Green | No |
| Controlled | N |