We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn about our cookie policy.
Cayman 4-oxo-27-TBDMS Withaferin A
List Price
$90.00
Your Price
$90.00
Cayman 4-oxo-27-TBDMS Withaferin A - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-28323-1
MFG.PART:
28323-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
4-oxo-27-TBDMS Withaferin A is a derivative of the steroidal lactone withaferin A (Item No. ) that has anticancer activity. It is cytotoxic to A2780 ovarian cancer cells (IC50 = 17 µM) but not to carboplatin-resistant A2780 (A2780/CP70) cells (IC50 = >100 µM). It is selective for A2780 cells over non-cancerous ARPE19 cells (IC50 = 1,660 µM). 4-oxo-27-TBDMS Withaferin A induces DNA fragmentation in A2780 cells.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(5β,6β,22R)-
CAS Number
1214886-31-3
Molecular Formula
C34H50O6Si
Formula Weight
582.9
Purity
≥98%
Formulation
A solution in ethanol
Solubility
- DMF: 5mg/mL
- DMSO: 5mg/mL
- DMSO:PBS (pH 7.2) (1:1): 0.5mg/mL
λmax
224 nm
SMILES
O=C(C=C1)[C@@]2(C)[C@@]([C@H]3C[C@]4([H])[C@]2([H])CC[C@@]5(C)[C@@]4([H])CC[C@]5([H])[C@H](C)[C@@]6([H])CC(C)=C(CO[Si](C)(C)C(C)(C)C)C(O6)=O)(O3)C1=O
InChi Code
InChI=1S/C34H50O6Si/c1-19-16-26(39-30(37)22(19)18-38-41(8,9)31(3,4)5)20(2)23-10-11-24-21-17-29-34(40-29)28(36)13-12-27(35)33(34,7)25(21)14-15-32(23,24)6/h12-13,20-21,23-26,29H,10-11,14-18H2,1-9H3/t20-,21-,23+,24-,25-,26+,29+,32+,33-,34+/m0/s1
InChi Key
RZWFBNOFUAHADD-VTYRCZOESA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-28323-1 |
|---|---|
| Supplier Part Number | 28323-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 1214886-31-3 |
| Energy Star | No |
| Green | No |
| Controlled | N |