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Cayman Hpa-12; Purity- Greater Than Or Equal To 98%; Size- 5 Mg;
List Price
$243.00
Your Price
$243.00
Cayman Hpa-12; Purity- Greater Than Or Equal To 98%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-28350-5
MFG.PART:
28350-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
HPA-12 is a ceramide analog and inhibitor of ceramide transfer protein (CERT)., It inhibits binding of a ceramide probe to the isolated steroidogenic acute regulatory protein-related lipid transfer (START) domain of CERT with an EC50 value of 4 μM in a TR-FRET assay. HPA-12 (2.5 μM) inhibits conversion of the fluorescent ceramide analog C5-DMB-Cer to C5-DMB-sphingomyelin in CHO and HeLa cells. It also inhibits sphingomyelin synthesis in wild-type, but not ATP-dependent ceramide transport-deficient, CHO cells when used at a concentration of 1 μM.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-[(1R,3S)-3-
CAS Number
383418-30-2
Synonyms
- (1R,3S)-HPA-12
Molecular Formula
C22H37NO3
Formula Weight
363.5
Purity
≥98%
Formulation
A solid
Solubility
- Chloroform: soluble
- DMSO: soluble
SMILES
OC[C@H](NC(CCCCCCCCCCC)=O)C[C@H](O)C1=CC=CC=C1
InChi Code
InChI=1S/C22H37NO3/c1-2-3-4-5-6-7-8-9-13-16-22(26)23-20(18-24)17-21(25)19-14-11-10-12-15-19/h10-12,14-15,20-21,24-25H,2-9,13,16-18H2,1H3,(H,23,26)/t20-,21+/m1/s1
InChi Key
YCAKBKAOFSILDC-RTWAWAEBSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-28350-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 28350-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 383418-30-2 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |