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Cayman Psora 4
List Price $587.00 Your Price $587.00
Cayman Psora 4 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-28389-25
MFG.PART: 28389-25
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Psora 4 is an inhibitor of voltage-gated potassium channels (Kv1.3; EC50 = 3 nM).1 It is selective for Kv1.3 over Kv1.1, Kv1.2, Kv1.4, Kv1.7, and Kv3.1 channels (EC50s = 62, 49, 202, 100, and 1,500 nM, respectively) but does inhibit the Kv1.5 channel (EC50 = 7.7 nM). Psora 4 selectively binds to the C-type inactivated state of the Kv1.3 channel and inhibits potassium current in a use-dependent manner. It has immunosuppressive activity, inhibiting proliferation of human and rat myelin-specific effector memory T cells in vitro (TEM cells; EC50s = 25 and 60 nM, respectively).
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-(4-phenyl
CAS Number
724709-68-6
Molecular Formula
C21H18O4
Formula Weight
334.4
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMSO: 10mg/mL
λmax
217, 251, 269, 310 nm
SMILES
O=C1C=CC2=C(OCCCCC3=CC=CC=C3)C4=C(OC=C4)C=C2O1
InChi Code
InChI=1S/C21H18O4/c22-20-10-9-16-19(25-20)14-18-17(11-13-23-18)21(16)24-12-5-4-8-15-6-2-1-3-7-15/h1-3,6-7,9-11,13-14H,4-5,8,12H2
InChi Key
JJAWGNIQEOFURP-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-28389-25 |
|---|---|
| Supplier Part Number | 28389-25 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 724709-68-6 |
| Energy Star | No |
| Green | No |
| Controlled | N |