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Cayman Cortexolone 17α-propionate
List Price $63.00 Your Price $63.00
Cayman Cortexolone 17α-propionate - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-28392-10
MFG.PART: 28392-10
UNSPSC: 12352200
Manufacturer: Cayman


Product Description
Cortexolone 17α-propionate is a peripherally selective androgen receptor antagonist. Cortexolone 17α-propionate binds to the androgen receptor (AR) and inhibits AR-regulated transcription in a reporter assay. It also inhibits androgen-regulated lipid synthesis in primary human sebocytes. Cortexolone 17α-propionate inhibits inflammatory cytokine production from primary human sebocytes and scalp dermal papilla cells., It inhibits testosterone propionate-induced flank organ enlargement in Syrian golden hamsters by 84% when administered topically at a dose of 400 μg/animal.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
21-hydroxy- 17-(1- oxopropoxy)- pregn-4-ene- 3,20-dione
CAS Number
19608-29-8
Synonyms
- CB-03-01
Molecular Formula
C24H34O5
Formula Weight
402.5
Purity
≥98%
Formulation
A solid
Solubility
- DMF: 20mg/mL
- DMSO: 10mg/mL
- Ethanol: 20mg/mL
- Ethanol:PBS (pH 7.2) (1:9): 0.1mg/mL
λmax
240, 295 nm
SMILES
O=C1CC[C@@]2(C)C(CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@]4(OC(CC)=O)C(CO)=O)=C1
InChi Code
InChI=1S/C24H34O5/c1-4-21(28)29-24(20(27)14-25)12-9-19-17-6-5-15-13-16(26)7-10-22(15,2)18(17)8-11-23(19,24)3/h13,17-19,25H,4-12,14H2,1-3H3/t17-,18+,19+,22+,23+,24+/m1/s1
InChi Key
GPNHMOZDMYNCPO-PDUMRIMRSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-28392-10 |
|---|---|
| Supplier Part Number | 28392-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 19608-29-8 |
| Energy Star | No |
| Green | No |
| Controlled | N |

