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Cayman Tetrazolyl Glycine
List Price $598.00 Your Price $598.00
Cayman Tetrazolyl Glycine - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-28408-50
MFG.PART: 28408-50
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Tetrazolyl glycine is an NMDA receptor agonist.1 It binds to rat brain membranes with IC50 values of 98 and 36 nM for [3H]CGS19755 and [3H]glutamate, respectively, in radioligand binding assays. It induces depolarization in rat cortical slices, an effect that is blocked by the NMDA receptor antagonist LY233053. It induces degeneration of GABAergic and cholinergic neurons in the striatum of adult rats and the formation of excitotoxic lesions and seizures in neonatal rats (ED50 = 0.071 mg/kg).2,1 Intrastriatal injection of tetrazolyl glycine (5 µM) increases COX-2 expression in striatal neurons and the vasculature near the striatal injection site in a mouse model of excitotoxicity-induced neuronal injury.3
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
α-amino-2H-tetrazole-5-acetic acid
CAS Number
138199-51-6
Synonyms
- Tet-Glycine
- LY285265
- DL-(Tetrazol-5-yl)glycine
Molecular Formula
C3H5N5O2
Formula Weight
143.1
Purity
≥95%
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- DMSO: 0.25mg/mL
- PBS (pH 7.2): 0.2mg/mL
SMILES
OC(C(N)C1=NN=NN1)=O
InChi Code
InChI=1S/C3H5N5O2/c4-1(3(9)10)2-5-7-8-6-2/h1H,4H2,(H,9,10)(H,5,6,7,8)
InChi Key
UKBRUIZWQZHXFL-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-28408-50 |
|---|---|
| Supplier Part Number | 28408-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 138199-51-6 |
| Energy Star | No |
| Green | No |
| Controlled | N |