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Cayman CCR2-RA-
List Price
$55.00
Your Price
$55.00
Cayman CCR2-RA-[R] - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-28423-1
MFG.PART:
28423-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
CCR2-RA-[R] is an allosteric antagonist of chemokine (C-C motif) receptor 2 (CCR2; IC50 = 103 nM).,, It inhibits [35S]GTPγS binding and β-arrestin recruitment induced by chemokine (C-C motif) ligand 2 (CCL2) in U2OS membranes and cells, respectively, expressing CCR2 (IC50s = 24 and 25 nM, respectively).
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(5R)-4-acetyl-
CAS Number
512177-83-2
Molecular Formula
C18H19ClFNO3
Formula Weight
351.8
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/mL
- DMSO: 30 mg/mL
- DMSO:PBS (pH 7.2) (1:3): 0.25 mg/mL
- Ethanol: 1 mg/mL
λmax
273 nm
SMILES
O=C1C(O)=C(C(C)=O)[C@@H](C2CCCCC2)N1C3=CC=C(Cl)C=C3F
InChi Code
InChI=1S/C18H19ClFNO3/c1-10(22)15-16(11-5-3-2-4-6-11)21(18(24)17(15)23)14-8-7-12(19)9-13(14)20/h7-9,11,16,23H,2-6H2,1H3/t16-/m1/s1
InChi Key
VQNLJXWZGVRLBA-MRXNPFEDSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-28423-1 |
|---|---|
| Supplier Part Number | 28423-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 512177-83-2 |
| Energy Star | No |
| Green | No |
| Controlled | N |