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Cayman Lupulone
List Price $49.00 Your Price $49.00
Cayman Lupulone - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-28481-1
MFG.PART: 28481-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Lupulone is a beta-acid that has been found in the hop plant, H. lupulus, and has diverse biological activities, including antibacterial, antioxidant, and anticarcinogenic properties.,, Lupulone is active against B. subtilis and S. aureus (MICs = 1 and 1.2 µg/mL, respectively), as well as T. b. brucei and L. M. mexicana (IC50s = 0.9 and 4.7 µg/mL, respectively)., It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. ) radicals in a cell-free assay and inhibits lipid peroxidation in rat brain homogenates (IC50s = 25 and 39 µM, respectively). It reduces proliferation, migration, and capillary tube formation in human umbilical vein endothelial cells (HUVECs) when used at concentrations ranging from 2.5 to 50 µg/mL. Lupulone (40 µg/mL) activates the extrinsic apoptotic death pathway in SW480 and SW620 colon cancer cells.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
3,5-dihydroxy-
CAS Number
468-28-0
Molecular Formula
C26H38O4
Formula Weight
414.6
Purity
≥95%
Formulation
A solid
Solubility
- Methanol: slightly soluble
SMILES
O=C1C(C/C=C(C)/C)(C/C=C(C)/C)C(O)=C(C(CC(C)C)=O)C(O)=C1C/C=C(C)/C
InChi Code
InChI=1S/C26H38O4/c1-16(2)9-10-20-23(28)22(21(27)15-19(7)8)25(30)26(24(20)29,13-11-17(3)4)14-12-18(5)6/h9,11-12,19,28,30H,10,13-15H2,1-8H3
InChi Key
WPVSVIXDXMNGGN-UHFFFAOYSA-N
Origin
Synthetic
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-28481-1 |
|---|---|
| Supplier Part Number | 28481-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | Canada |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 468-28-0 |
| Energy Star | No |
| Green | No |
| Controlled | N |