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Cayman meso-2,3-Dimercaptosuccinic Acid
List Price $36.00 Your Price $36.00
Cayman meso-2,3-Dimercaptosuccinic Acid - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-28515-1
MFG.PART: 28515-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
meso-2,3-Dimercaptosuccinic acid is a heavy metal chelator. It reverses sodium arsenite-induced inhibition of pyruvate dehydrogenase (PDH) in mouse kidney homogenates (EC50 = 0.25 mm). meso-2,3-Dimercaptosuccinic acid decreases cisplatin-induced increases in serum levels of platinum and blood urea nitrogen (BUN), as well as apoptosis in renal tubules of mice when administered at a dose of 100 µM/kg. meso-2,3-Dimercaptosuccinic acid (90 mg/kg) decreases elevations in the activity of catalase and glucose-6-phosphate dehydrogenase (G6PDH) in RBCs from lead-exposed rats, and decreases the levels of lead in the cerebellum, hippocampus, liver, kidney, and blood in rats when administered at a dose of 100 mg/kg., It decreases immobility time in the forced swim test in lead-exposed male, but not female, mice when administered at a dose of 50 mg/kg. Formulations containing meso-2,3-dimercaptosuccinic acid have been used in the treatment of heavy metal poisoning.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(2R,3S)-rel-
CAS Number
304-55-2
Synonyms
- DMSA
- Succimer
Molecular Formula
C4H6O4S2
Formula Weight
182.2
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMF: 10mg/mL
- DMSO: 10 mg/mL
- DMSO:PBS (pH 7.2) (1:8): 0.1 mg/mL
SMILES
OC([C@@H](S)[C@@H](S)C(O)=O)=O
InChi Code
InChI=1S/C4H6O4S2/c5-3(6)1(9)2(10)4(7)8/h1-2,9-10H,(H,5,6)(H,7,8)/t1-,2+
InChi Key
ACTRVOBWPAIOHC-XIXRPRMCSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-28515-1 |
|---|---|
| Supplier Part Number | 28515-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 304-55-2 |
| Energy Star | No |
| Green | No |
| Controlled | N |