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Cayman 17R(18S)-EpETE
List Price
$98.00
Your Price
$98.00
Cayman 17R(18S)-EpETE - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-28630-50
MFG.PART:
28630-50
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
17R(18S)-EpETE is an oxylipin and a cytochrome P450 metabolite of eicosapentaenoic acid (EPA; Item Nos. 90110 | 90110.1 | 21908).1,2 17R(18S)-EpETE is an activator of large-conductance calcium-activated potassium (KCa1.1/BK) channels, increasing the potassium current amplitude by 15-fold in isolated rat cerebral artery vascular smooth muscle cells (VSMCs) at +60 mV when used at a concentration of 50 nM.2 It has negative chronotropic effects in isolated neonatal rat cardiomyocytes (NRCMs; EC50 = ~1-2 nM) and prevents calcium-induced increases in the spontaneous beating of NRCMs.3,4
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
16-[(2R,3S)-
CAS Number
725246-18-4
Synonyms
- 17R,18S-EEQ
- 17R,18S-epoxy Eicosatetraenoic Acid
Molecular Formula
C20H30O3
Formula Weight
318.5
Purity
≥95%
Formulation(Request formulation change)
A solution in ethanol
Solubility(Learn about Variance in Solubility)
- Ethanol: soluble
SMILES
CC[C@H]1[C@H](O1)C/C=C\C/C=C\C/C=C\C/C=C\CCCC(O)=O
InChi Code
InChI=1S/C20H30O3/c1-2-18-19(23-18)16-14-12-10-8-6-4-3-5-7-9-11-13-15-17-20(21)22/h3,5-6,8-9,11-12,14,18-19H,2,4,7,10,13,15-17H2,1H3,(H,21,22)/b5-3-,8-6-,11-9-,14-12-/t18-,19+/m0/s1
InChi Key
GPQVVJQEBXAKBJ-VDTDYMMTSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-28630-50 |
|---|---|
| Supplier Part Number | 28630-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 725246-18-4 |
| Energy Star | No |
| Green | No |
| Controlled | N |