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Cayman Tiratricol
List Price $402.00 Your Price $402.00
Cayman Tiratricol - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-28729-1
MFG.PART: 28729-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Tiratricol is a metabolite of 3,3,5-triiodo-L-thyronine (Item No. ) and an agonist of the thyroid hormone receptors TRα and TRβ (EC50s = 1.81 and 4.13 nM, respectively, in reporter assays). In vivo, tiratricol (50 or 400 ng/g) stimulates cerebellar Purkinje cell dendritogenesis and cortical myelination in Mct8/Oatp1c1 double knockout mice. It reduces goiter induced by methimazole (Item No. ) in rats when administered at a dose of 25 μg per animal. Tiratricol also decreases toll-like receptor 2 (TLR2) levels and the phosphorylation of Akt and MAPK in HEK-Blue™ cells expressing human TLR2 and reduces liver tissue necrosis in a mouse model of hepatitis induced by concanavalin A (Item No. )..
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-(4-hydroxy-
CAS Number
51-24-1
Synonyms
- 3,3′,5-Triiodothyroacetic acid
Molecular Formula
C14H9I3O4
Formula Weight
621.9
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/mL
- DMSO: 30 mg/mL
- Ethanol: 30 mg/mL
λmax
210, 227 nm
SMILES
OC(CC1=CC(I)=C(OC2=CC=C(O)C(I)=C2)C(I)=C1)=O
InChi Code
InChI=1S/C14H9I3O4/c15-9-6-8(1-2-12(9)18)21-14-10(16)3-7(4-11(14)17)5-13(19)20/h1-4,6,18H,5H2,(H,19,20)
InChi Key
UOWZUVNAGUAEQC-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-28729-1 |
|---|---|
| Supplier Part Number | 28729-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 51-24-1 |
| Energy Star | No |
| Green | No |
| Controlled | N |