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Cayman Atreleuton
List Price $36.00 Your Price $36.00
Cayman Atreleuton - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-28736-1
MFG.PART: 28736-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Atreleuton is an inhibitor of 5-lipoxygenase (5-LO; IC50 = 23 nM in rat basophil leukemia cell lysates).1 It inhibits leukotriene B4 (LTB4; Item No. 20110) formation induced by A23187 (Item Nos. 11016 | 22030) in isolated human whole blood (IC50 = 160 nM). Atreleuton inhibits LTE4 and LTB4 biosynthesis in the peritoneal cavity in a rat model of anaphylaxis (ED50s = 1.4 and 0.6 mg/kg, respectively) and bronchoconstriction induced by arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) in anesthetized guinea pigs (ED50 = 3 mg/kg).2
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-[(1R)-3-[5-
CAS Number
154355-76-7
Synonyms
- A-85761.0
- ABT-761
- VIA-2291
Molecular Formula
C16H15FN2O2S
Formula Weight
318.4
Purity
≥98%
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- Methanol: soluble
SMILES
FC1=CC=C(CC2=CC=C(C#C[C@H](N(C(N)=O)O)C)S2)C=C1
InChi Code
InChI=1S/C16H15FN2O2S/c1-11(19(21)16(18)20)2-7-14-8-9-15(22-14)10-12-3-5-13(17)6-4-12/h3-6,8-9,11,21H,10H2,1H3,(H2,18,20)/t11-/m1/s1
InChi Key
MMSNEKOTSJRTRI-LLVKDONJSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-28736-1 |
|---|---|
| Supplier Part Number | 28736-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 154355-76-7 |
| Energy Star | No |
| Green | No |
| Controlled | N |