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Cayman Anthrax Lethal Factor (recombinant from Bacillus anthracis), Native Sequence (LF-A)
List Price $534.00 Your Price $534.00
Cayman Anthrax Lethal Factor (recombinant from Bacillus anthracis), Native Sequence (LF-A) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-28874-200
MFG.PART: 28874-200
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Anthrax lethal factor is one component of a tripartite protein toxin secreted into host systems during anthrax infection by B. anthracis. The toxin is a mixture of three protein components: Lethal factor, edema factor, and protective antigen. Lethal factor is a zinc-dependent metalloprotease that disrupts MAPK signaling by cleaving MAPK kinases near the N-terminal end. It requires protective antigen (PA), but not edema factor (EF), for its lethality. LF-A, in combination with PA, is lethal to RAW 264.7 cells (EC50 = 1.2 ng/mL) and rats when administered at doses of 10 and 100 µg/animal, respectively.
WARNING This product is not for human or veterinary use.
Technical Information
Purity
≥95% estimated by SDS
Formulation
Each vial contains 0.2 mg of recombinant lethal factor from Bacillus anthracis, native sequence in 0.2 mL of 5 mm HEPES, 50 mm NaCl, pH 7.5.
Origin
Bacterium/Bacillus anthracis
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-28874-200 |
|---|---|
| Supplier Part Number | 28874-200 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| Controlled | N |