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Cayman H-Ile-Pro-Pro-Oh (Trifluoroacetate Salt)
List Price
$257.00
Your Price
$257.00
Cayman H-Ile-Pro-Pro-Oh (Trifluoroacetate Salt) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-28899-50
MFG.PART:
28899-50
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
H-Ile-Pro-Pro-OH (IPP) is a peptide inhibitor of angiotensin converting enzyme (ACE; IC50 = 5 µM).1 It inhibits acetylcholine-induced nitric oxide (NO) production in human umbilical vein endothelial cells (HUVECs) when used at a concentration of 1 µM and induces vasorelaxation in precontracted isolated rat aortic rings.2 IPP (0.3 mg/kg) decreases systolic blood pressure in spontaneously hypertensive, but not normotensive, rats.3 Dietary administration of IPP reduces plasma levels of total cholesterol, HDL-cholesterol, and triglycerides, mRNA expression of IL-6 and IL-1β, and aortic arch intimal thickening and atherosclerotic plaque formation in ApoE-/- mice.4
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
L-isoleucyl- L-prolyl-L- proline
Synonyms
- IPP
Molecular Formula
C16H27N3O4 • XCF3COOH
Formula Weight
325.4
Purity
≥95%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 25 mg/ml
- DMSO: 25 mg/ml
- Ethanol: 10 mg/ml
- PBS (pH 7.2): 10 mg/ml
SMILES
C[C@H]([C@H](N)C(N1CCC[C@H]1C(N2CCC[C@H]2C(O)=O)=O)=O)CC.FC(F)(C(O)=O)F
InChi Code
InChI=1S/C16H27N3O4.C2HF3O2/c1-3-10(2)13(17)15(21)18-8-4-6-11(18)14(20)19-9-5-7-12(19)16(22)23;3-2(4,5)1(6)7/h10-13H,3-9,17H2,1-2H3,(H,22,23);(H,6,7)/t10-,11-,12-,13-;/m0./s1
InChi Key
KUKQSXVYCGOYJM-KRBYAKJKSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-28899-50 |
|---|---|
| Featured | No |
| Supplier Part Number | 28899-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |