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Cayman Saquinavir-d9
List Price $395.00 Your Price $395.00
Cayman Saquinavir-d9 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-28906-1
MFG.PART: 28906-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Saquinavir-d9 is intended for use as an internal standard for the quantification of saquinavir (Item No. ) by GC- or LC-MS. Saquinavir is an HIV protease inhibitor (Kis = 0.12 and <0.1 nM for HIV-1 and HIV-2 protease, respectively). It is selective for HIV-1 and HIV-2 protease over human aspartic proteases, renin, pepsin, pepsinogen C, cathepsin D, and cathepsin E at 10 µM. Saquinavir inhibits replication of clinical isolates of HIV-1 in a variety of cell-based assays and has antiviral activity against HIV-1 in infected C8166 cells (IC50 = 2 nM)., It also inhibits the activity of the severe acute respiratory coronavirus 2 (SARS-CoV-2) main protease (Mpro), also known as 3C-like protease (3CLpro), with an IC50 value of 9.92 µM.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(2S)-N1-[(1S,
CAS Number
1356355-11-7
Molecular Formula
C38H41D9N6O5
Formula Weight
679.9
Purity
≥99% deuterated forms (d1-d9)
Formulation
A solid
Solubility
- Chloroform: soluble
- Methanol: soluble
SMILES
O=C(N[C@@H](CC(N)=O)C(N[C@@H](CC1=CC=CC=C1)[C@H](O)CN2C[C@](CCCC3)([H])[C@]3([H])C[C@H]2C(NC(C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])=O)=O)C4=NC(C=CC=C5)=C5C=C4
InChi Code
InChI=1S/C38H50N6O5/c1-38(2,3)43-37(49)32-20-26-14-7-8-15-27(26)22-44(32)23-33(45)30(19-24-11-5-4-6-12-24)41-36(48)31(21-34(39)46)42-35(47)29-18-17-25-13-9-10-16-28(25)40-29/h4-6,9-13,16-18,26-27,30-33,45H,7-8,14-15,19-23H2,1-3H3,(H2,39,46)(H,41,48)(H,42,47)(H,43,49)/t26-,27+,30-,31-,32-,33+/m0/s1/i1D3,2D3,3D3
InChi Key
QWAXKHKRTORLEM-ABBOPLMISA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-28906-1 |
|---|---|
| Supplier Part Number | 28906-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | Canada |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1356355-11-7 |
| Energy Star | No |
| Green | No |
| Controlled | N |