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Cayman SMCC
List Price $63.00 Your Price $63.00
Cayman SMCC - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-28955-50
MFG.PART: 28955-50
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
SMCC is a heterobifunctional cross-linking reagent that contains an amine-reactive N-hydroxysuccinimide ester and a sulfhydryl-reactive maleimide group that can be used in the conjugation of proteins.1,2,3 It has been used to cross-link the anticancer agent DM1 (mertansine; Item No. 22483) to an IgG1 monoclonal antibody to form the antibody-drug conjugate DM1-SMCC (Item No. 23926).4 Immunization of mice with SMCC-coupled keyhole limpet hemocyanin (KLH) antigen and syngeneic splenocytes increases the percentage of proliferating T cells in isolated splenocytes from recipient mice compared to mice immunized with KLH and the adjuvant LPS.3
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-[(2,5-
CAS Number
64987-85-5
Synonyms
- NSC 344483
- Succinimidyl 4-(N-maleimidomethyl)cyclohexan-1-carboxylate
Molecular Formula
C16H18N2O6
Formula Weight
334.3
Purity
≥98%
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- DMF: 15mg/mL
- DMF:PBS (pH 7.2) (1:4): 0.2mg/mL
- DMSO: 10mg/mL
λmax
217 nm
SMILES
O=C(ON1C(CCC1=O)=O)C(CC2)CCC2CN(C(C=C3)=O)C3=O
InChi Code
InChI=1S/C16H18N2O6/c19-12-5-6-13(20)17(12)9-10-1-3-11(4-2-10)16(23)24-18-14(21)7-8-15(18)22/h5-6,10-11H,1-4,7-9H2
InChi Key
JJAHTWIKCUJRDK-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-28955-50 |
|---|---|
| Supplier Part Number | 28955-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 64987-85-5 |
| Energy Star | No |
| Green | No |
| Controlled | N |