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Cayman UNC2881
List Price $853.00 Your Price $853.00
Cayman UNC2881 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-29012-50
MFG.PART: 29012-50
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
UNC2881 is an inhibitor of Mer (IC50 = 4.3 nM), a member of the TAM family of receptor tyrosine kinases.1 It is selective for Mer over the remaining TAM family members Axl and TYRO3 (IC50s = 360 and 250 nM, respectively). UNC2881 inhibits phosphorylation of Mer in 697 B-ALL acute lymphoblastic leukemia cells (IC50 = 21.9 nM). It inhibits platelet aggregation and ATP release induced by type I equine fibrillar collagen in isolated human platelet-rich plasma when used at a concentration of 3 μM.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2-(butyl
CAS Number
1493764-08-1
Molecular Formula
C25H33N7O2
Formula Weight
463.6
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 30 mg/mL
- DMSO: 30 mg/mL
- DMSO:PBS (pH 7.2) (1:3): 0.25 mg/mL
- Ethanol: 1 mg/mL
λmax
232, 263, 309 nm
SMILES
O[C@H]1CC[C@H](NC2=NC(NCCCC)=NC=C2C(NCC3=CC=C(N4C=NC=C4)C=C3)=O)CC1
InChi Code
InChI=1S/C25H33N7O2/c1-2-3-12-27-25-29-16-22(23(31-25)30-19-6-10-21(33)11-7-19)24(34)28-15-18-4-8-20(9-5-18)32-14-13-26-17-32/h4-5,8-9,13-14,16-17,19,21,33H,2-3,6-7,10-12,15H2,1H3,(H,28,34)(H2,27,29,30,31)/t19-,21-
InChi Key
NPVXOWLPOFYACO-XUTJKUGGSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-29012-50 |
|---|---|
| Supplier Part Number | 29012-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1493764-08-1 |
| Energy Star | No |
| Green | No |
| Controlled | N |