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Cayman 20(S)-Protopanaxatriol
List Price $40.00 Your Price $40.00
Cayman 20(S)-Protopanaxatriol - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-29073-1
MFG.PART: 29073-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
20(S)-Protopanaxatriol is an active aglycone metabolite of various panaxatriol ginsenosides, including ginsenoside Re (Item No. ), ginsenoside RF (Item No. ), ginsenoside Rg1 (Item No. ), ginsenoside Rg2 (Item No. ), and ginsenoside RH1 (Item No. ). It is cytotoxic to HL-60 cancer cells (IC50 = 16 µM). 20(S)-Protopanaxatriol inhibits the proliferation of human umbilical vein endothelial cells (HUVECs; EC50 = 6.64 µg/mL). It inhibits LPS-induced increases in the protein levels of COX-2 and inducible nitric oxide synthase (iNOS) and decreases LPS-induced NF-κB activity in RAW 264.7 cells when used at concentrations ranging from 1 to 20 µM.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(3β,6α,12β)-
CAS Number
34080-08-5
Synonyms
- 20(S)-APPT
- 20(S)-PPT
Molecular Formula
C30H52O4
Formula Weight
476.7
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/mL
- DMSO: 30 mg/mL
- Ethanol: 30 mg/mL
- Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/mL
SMILES
CC1(C)[C@@H](O)CC[C@@]2(C)[C@@]1([H])[C@@H](O)C[C@]3(C)[C@]2([H])C[C@@H](O)[C@@]4([H])[C@@]3(C)CC[C@]4([H])[C@@](C)(O)CC/C=C(C)/C
InChi Code
InChI=1S/C30H52O4/c1-18(2)10-9-13-30(8,34)19-11-15-28(6)24(19)20(31)16-22-27(5)14-12-23(33)26(3,4)25(27)21(32)17-29(22,28)7/h10,19-25,31-34H,9,11-17H2,1-8H3/t19-,20+,21-,22+,23-,24-,25-,27+,28+,29+,30-/m0/s1
InChi Key
SHCBCKBYTHZQGZ-CJPZEJHVSA-N
Origin
Plant/Ginseng Radix et Rhizoma
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-29073-1 |
|---|---|
| Supplier Part Number | 29073-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 34080-08-5 |
| Energy Star | No |
| Green | No |
| Controlled | N |