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Cayman Benznidazole
List Price
$796.00
Your Price
$796.00
Cayman Benznidazole - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-29090-250
MFG.PART:
29090-250
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Benznidazole is an orally bioavailable antiprotozoal agent.1 It is a 2-nitroimidazole prodrug that becomes active when the nitro group is reduced within the parasite.2 It inhibits the growth of the parasites T. cruzi, T. vaginalis, g. lamblia, and E. histolytica (IC50s = 8.1, 18.62, 22.58, and 4.27 μM, respectively).3,4 It also inhibits clonogenic growth of human C33A cervical and KNS42 glioblastoma cancer cells under hypoxic, but not normoxic, conditions when used at a concentration of 100 μM.5 Benznidazole (100 mg/kg per day) decreases T. cruzi blood parasitemia to below detectable levels in a mouse model of chronic stable Chagas disease.1 Formulations containing benznidazole have been used in the treatment of Chagas disease caused by T. cruzi.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2-nitro-N-
CAS Number
22994-85-0
Synonyms
- NSC 299972
- Ro 07-1051
Molecular Formula
C12H12N4O3
Formula Weight
260.3
Purity
≥95%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 30 mg/mL
- DMSO: 30 mg/mL
- DMSO:PBS (pH 7.2) (1:3): 0.25 mg/mL
λmax
316 nm
SMILES
O=C(CN1C=CN=C1[N+]([O-])=O)NCC2=CC=CC=C2
InChi Code
InChI=1S/C12H12N4O3/c17-11(14-8-10-4-2-1-3-5-10)9-15-7-6-13-12(15)16(18)19/h1-7H,8-9H2,(H,14,17)
InChi Key
CULUWZNBISUWAS-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-29090-250 |
|---|---|
| Supplier Part Number | 29090-250 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 22994-85-0 |
| Energy Star | No |
| Green | No |
| Controlled | N |