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Cayman CINPA1
List Price $36.00 Your Price $36.00
Cayman CINPA1 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-29110-1
MFG.PART: 29110-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
CINPA1 is a constitutive androstane receptor (CAR) antagonist (IC50 = 70 nM in a reporter assay). It is selective for CAR over the nuclear receptors GR, FXR, LXRα, LXRβ, PPARγ, RXRα, and RXRβ at 18 μM, but also antagonizes the human pregnane X receptor (PXR; IC50 = 6.6 μM). CINPA1 (0.3-5 μM) inhibits CAR transactivation of CYP2B6 induced by CITCO (Item No. ) in primary human hepatocytes.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
[5-[(diethyl
CAS Number
102636-74-8
Molecular Formula
C23H29N3O3
Formula Weight
395.5
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMSO: 100 mm
- Ethanol: 100 mm
SMILES
O=C(CN(CC)CC)N1C(C=C(NC(OCC)=O)C=C2)=C2CCC3=C1C=CC=C3
InChi Code
InChI=1S/C23H29N3O3/c1-4-25(5-2)16-22(27)26-20-10-8-7-9-17(20)11-12-18-13-14-19(15-21(18)26)24-23(28)29-6-3/h7-10,13-15H,4-6,11-12,16H2,1-3H3,(H,24,28)
InChi Key
AYQBYSPEGRYKFA-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-29110-1 |
|---|---|
| Supplier Part Number | 29110-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 102636-74-8 |
| Energy Star | No |
| Green | No |
| Controlled | N |