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Cayman ACY-775
List Price
$36.00
Your Price
$36.00
Cayman ACY-775 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-29198-1
MFG.PART:
29198-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
ACY-775 is an inhibitor of histone deacetylase 6 (HDAC6; IC50 = 0.0075 µM). It is selective for HDAC6 over HDAC1, HDAC2, and HDAC3 (IC50s = 2.1, 2.5, and 11.2 µM, respectively). ACY-775 (2.5 µM) increases α-tubulin acetylation at lysine 40 in RN46A-B14 serotonergic cells. It increases the distance traveled in the center of the open field test and decreases immobility time in the tail suspension test, indicating anxiolytic- and antidepressant-like activities, respectively, in mice when administered at a dose of 50 mg/kg.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2-[[1-(3-fluoro
CAS Number
1375466-18-4
Molecular Formula
C17H19FN4O2
Formula Weight
330.4
Purity
≥95%
Formulation
A solid
Solubility
- DMF: 20 mg/mL
- DMF:PBS (pH 7.2) (1:4): 0.2 mg/mL
- DMSO: 15 mg/mL
- Ethanol: 3 mg/mL
λmax
269 nm
SMILES
O=C(NO)C1=CN=C(NC2(C3=CC=CC(F)=C3)CCCCC2)N=C1
InChi Code
InChI=1S/C17H19FN4O2/C18-14-6-4-5-13(9-14)17(7-2-1-3-8-17)21-16-19-10-12(11-20-16)15(23)22-24/h4-6,9-11,24H,1-3,7-8H2,(H,22,23)(H,19,20,21)
InChi Key
IYBURCQQEUNLDL-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-29198-1 |
|---|---|
| Supplier Part Number | 29198-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1375466-18-4 |
| Energy Star | No |
| Green | No |
| Controlled | N |