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Cayman BX-517
List Price $215.00 Your Price $215.00
Cayman BX-517 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-29238-10
MFG.PART: 29238-10
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
BX-517 is an inhibitor of the serine/threonine kinase 3-phosphoinositide-dependent protein kinase 1 (PDK1; IC50 = 6 nM). It binds to the ATP binding pocket of PDK1, inhibits Akt2 activation induced by PDK1 in a cell-free assay (IC50 = 20 nM), and inhibits Akt phosphorylation in PC3 cells.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-[2,3-
CAS Number
850717-64-5
Synonyms
- PDK1 Inhibitor II
Molecular Formula
C15H14N4O2
Formula Weight
282.3
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 14 mg/mL
- DMSO: 20 mg/mL
- DMSO:PBS (pH 7.2) (1:3): 0.25 mg/mL
- Ethanol: Partially soluble
λmax
221, 279, 297, 308, 396 nm
SMILES
O=C1/C(C2=CC(NC(N)=O)=CC=C2N1)=C(C3=CC=CN3)/C
InChi Code
InChI=1S/C15H14N4O2/c1-8(11-3-2-6-17-11)13-10-7-9(18-15(16)21)4-5-12(10)19-14(13)20/h2-7,17H,1H3,(H,19,20)(H3,16,18,21)/b13-8-
InChi Key
DFURSNCTQGJRRX-JYRVWZFOSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-29238-10 |
|---|---|
| Supplier Part Number | 29238-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 850717-64-5 |
| Energy Star | No |
| Green | No |
| Controlled | N |