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Cayman Snap-25 (Phospho-Ser187) Polyclonal Antibody, 100 L
List Price
$359.00
Your Price
$359.00
Cayman Snap-25 (Phospho-Ser187) Polyclonal Antibody, , 100 L - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-29294-100
MFG.PART:
29294-100
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Moexipril-d5 intended for use as an internal standard for the quantification of moexipril (Item No. ) by GC- or LC-MS. Moexipril is a prodrug form of the angiotensin converting enzyme (ACE) inhibitor moexiprilat. It is converted to moexiprilat in vivo by side chain ester hydrolysis. Moexipril inhibits ACE in a cell-free assay (IC50 = 2.7 µM for the rabbit enzyme). It also inhibits phosphodiesterase 4 (IC50s = 38, 160, and 230 µM for PDE4B2, PDE4A5 and PDE4D5, respectively). Moexipril (0.1-30 mg/kg per day) reduces blood pressure in spontaneously hypertensive rats. It also reduces infarct volume in a rat model of focal cerebral ischemia when used at a concentration of 0.01 mg/kg.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(S)-2-(((S)-1- ethoxy-1-oxo- 4-(phenyl-d5) butan-2-yl)- L-alanyl)-6, 7-dimethoxy- 1,2,3,4-tetra hydroiso quinoline-3- carboxylic acid
CAS Number
1356929-49-1
Molecular Formula
C27H29D5N2O7
Formula Weight
503.6
Purity
≥99% deuterated forms (d1-d5)
Formulation
A solid
Solubility
- DMSO: soluble
- Methanol: soluble
SMILES
[2H]C1=C([2H])C([2H])=C([2H])C([2H])=C1CC[C@@H](C(OCC)=O)N[C@@H](C)C(N2CC3=CC(OC)=C(OC)C=C3C[C@H]2C(O)=O)=O
InChi Code
InChI=1S/C27H34N2O7/c1-5-36-27(33)21(12-11-18-9-7-6-8-10-18)28-17(2)25(30)29-16-20-15-24(35-4)23(34-3)14-19(20)13-22(29)26(31)32/h6-10,14-15,17,21-22,28H,5,11-13,16H2,1-4H3,(H,31,32)/t17-,21-,22-/m0/s1/i6D,7D,8D,9D,10D
InChi Key
UWWDHYUMIORJTA-SBCWFVTISA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-29294-100 |
|---|---|
| Featured | No |
| Supplier Part Number | 29294-100 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |