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Cayman Ly334370 (Hydrochloride)
List Price
$49.00
Your Price
$49.00
Cayman Ly334370 (Hydrochloride) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-29481-1
MFG.PART:
29481-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
LY334370 is an agonist of the serotonin (5-HT) receptor subtype 5-HT1F (Kd = 0.446 nM). It is selective for 5-HT1F over other G protein-coupled 5-HT receptor subtypes with Ki values ranging from 16.4 to greater than 3,000 nM in radioligand binding assays. LY334370 inhibits forskolin-induced cAMP accumulation in mouse L-M(TK-) cell membranes expressing the recombinant human 5-HT1F receptor (EC50 = 1.51 nM). It decreases electrically stimulated extravasation of plasma proteins in the dura mater in a guinea pig trigeminal nerve model of migraine headache.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-fluoro-N-
CAS Number
199673-74-0
Molecular Formula
C21H22FN3O • HCl
Formula Weight
387.9
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMSO: soluble
- Water: soluble
λmax
228, 267 nm
SMILES
FC1=CC=C(C(NC2=CC(C(C3CCN(C)CC3)=CN4)=C4C=C2)=O)C=C1.Cl
InChi Code
InChI=1S/C21H22FN3O.ClH/c1-25-10-8-14(9-11-25)19-13-23-20-7-6-17(12-18(19)20)24-21(26)15-2-4-16(22)5-3-15;/h2-7,12-14,23H,8-11H2,1H3,(H,24,26);1H
InChi Key
DGPDGAPZTPSHBL-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-29481-1 |
|---|---|
| Featured | No |
| Supplier Part Number | 29481-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 199673-74-0 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |