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Cayman PD 90780 (hydrate)
List Price
$213.00
Your Price
$213.00
Cayman PD 90780 (hydrate) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-29488-10
MFG.PART:
29488-10
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
PD 90780 is an inhibitor of the interaction between NGF and the p75 NGF receptor (NGFR).1 It binds to NGF (KD = 25.83 μM) and inhibits NGF binding to the extracellular domain of p75 NGFR (IC50 = 220 nM), as well as to Q1-CHO Cells expressing full-length human p75 NGFR (IC50 = 300 nM).1,2 PD 90780 inhibits NGF-dependent differentiation of PC12 cells (IC50 = 33.22 μM).2
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
7-(benzoyl amino)-4,9- dihydro-4- methyl-9-oxo- pyrazolo [5,1-b] quinazoline- 2-carboxylic acid, hydrate
Molecular Formula
C19H14N4O4 • XH2O
Formula Weight
362.3
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMSO: 36 mg/mL
λmax
236, 287, 312 nm
SMILES
O=C(NC1=CC=C(N(C)C2=CC(C(O)=O)=NN2C3=O)C3=C1)C4=CC=CC=C4.O
InChi Code
InChI=1S/C19H14N4O4.H2O/c1-22-15-8-7-12(20-17(24)11-5-3-2-4-6-11)9-13(15)18(25)23-16(22)10-14(21-23)19(26)27;/h2-10H,1H3,(H,20,24)(H,26,27);1H2
InChi Key
CPXCLWYHBRAPEA-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-29488-10 |
|---|---|
| Supplier Part Number | 29488-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| Controlled | N |