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Cayman Decynium-22
List Price $190.00 Your Price $190.00
Cayman Decynium-22 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-29494-1
MFG.PART: 29494-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Decynium-22 is an inhibitor of monoamine transporters and organic cation transporters (OCTs). It inhibits the plasma membrane monoamine, serotonin (5-HT), norepinephrine, and dopamine monoamine transporters (IC50s = 1.1, 7.9, 30, and 12.9 µM, respectively), and OCT2 and OCT3 (IC50s = 10 and 0.2 µM, respectively) in radioligand binding assays. Decynium-22 also inhibits binding of the α1-adrenergic receptor antagonist prazosin (Item No. ) in mouse hippocampal homogenates (IC50 = 60 nM). It decreases the time stress-sensitive Wistar Kyoto, but not stress-resistant Long-Evans, rats spend immobile in the forced swim test, indicating antidepressant-like activity, when administered at doses of 1 and 10 µg/kg.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
1-ethyl-2-
CAS Number
977-96-8
Synonyms
- 1,1′-Diethyl-2,2′-Cyanine
Molecular Formula
C23H23N2 • I
Formula Weight
454.4
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMSO: 1 mg/mL
- DMSO:PBS (pH 7.2) (1:3): 0.25 mg/mL
λmax
226, 491, 524 nm
SMILES
CCN(C1=CC=CC=C1C=C/2)C2=C\C3=[N+](CC)C4=C(C=CC=C4)C=C3.[I-]
InChi Code
InChI=1S/C23H23N2.HI/c1-3-24-20(15-13-18-9-5-7-11-22(18)24)17-21-16-14-19-10-6-8-12-23(19)25(21)4-2;/h5-17H,3-4H2,1-2H3;1H/q+1;/p-1
InChi Key
GMYRVMSXMHEDTL-UHFFFAOYSA-M
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-29494-1 |
|---|---|
| Supplier Part Number | 29494-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 977-96-8 |
| Energy Star | No |
| Green | No |
| Controlled | N |