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Cayman Tasosartan
List Price $753.00 Your Price $753.00
Cayman Tasosartan - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-29495-250
MFG.PART: 29495-250
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Tasosartan is an angiotensin II type 2 (AT2) receptor antagonist (IC50 = 1.2 nM in rat adrenal gland membranes).1 It also binds to the AT1 receptor (Ki = 46.6 nM in rat liver epithelial cells).2 Tasosartan (3 mg/kg, intraduodenally) reduces the AT2-induced pressor response in rats.3 It also decreases mean arterial pressure in a rat model of hypertension induced by renal artery constriction when administered intragastrically or intravenously at doses of 1 and 3 mg/kg.1
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
5,8-dihydro-
CAS Number
145733-36-4
Synonyms
- WAY-ANA-756
Molecular Formula
C23H21N7O
Formula Weight
411.5
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 20 mg/mL
- DMF:PBS (pH 7.2) (1:1): 0.5 mg/mL
- DMSO: 14 mg/mL
- Ethanol: 2 mg/mL
λmax
251 nm
SMILES
CC1=NC(C)=C(CCC(N2CC3=CC=C(C4=CC=CC=C4C5=NN=NN5)C=C3)=O)C2=N1
InChi Code
InChI=1S/C23H21N7O/c1-14-18-11-12-21(31)30(23(18)25-15(2)24-14)13-16-7-9-17(10-8-16)19-5-3-4-6-20(19)22-26-28-29-27-22/h3-10H,11-13H2,1-2H3,(H,26,27,28,29)
InChi Key
ADXGNEYLLLSOAR-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-29495-250 |
|---|---|
| Supplier Part Number | 29495-250 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 145733-36-4 |
| Energy Star | No |
| Green | No |
| Controlled | N |