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Cayman 7-keto Lithocholic Acid
List Price $93.00 Your Price $93.00
Cayman 7-keto Lithocholic Acid - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-29546-1
MFG.PART: 29546-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
7-keto Lithocholic acid is an intermediate in the synthesis of the secondary bile acid ursodeoxycholic acid (Item No. 15121) by intestinal bacteria in humans.1,2 It is formed from chenodeoxycholic acid (Item No. 10011286) in B. intestinalis isolated from human feces.1 Venous infusion of 7-keto lithocholic acid (1.2 µmol/min per 100 g body weight) increases the bile flow rate and the concentration of bile bicarbonate in rats.3 7-keto Lithocholic acid levels are decreased in rat feces in a model of adenine-induced chronic renal failure.4 Fecal levels are also reduced in patients with liver cirrhosis or hepatocellular carcinoma.5
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(3α,5β)-3-
CAS Number
4651-67-6
Synonyms
- 7-KLCA
- 7-keto LCA
- 7-oxo LCA
- 7-keto Lithocholate
- 7-oxo Lithocholate
- 7-oxo Lithocholic Acid
- NSC 226118
Molecular Formula
C24H38O4
Formula Weight
390.6
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 30 mg/mL
- DMSO: 30 mg/mL
- Ethanol: 30 mg/mL
- Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/mL
SMILES
C[C@H](CCC(O)=O)[C@@]1([H])CC[C@@]2([H])[C@]3([H])C(C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C)=O
InChi Code
InChI=1S/C24H38O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(25)12-15(23)13-20(22)26/h14-19,22,25H,4-13H2,1-3H3,(H,27,28)/t14-,15+,16-,17-,18+,19+,22+,23+,24-/m1/s1
InChi Key
DXOCDBGWDZAYRQ-AURDAFMXSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-29546-1 |
|---|---|
| Supplier Part Number | 29546-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 4651-67-6 |
| Energy Star | No |
| Green | No |
| Controlled | N |