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Cayman Ro 41-0960
List Price
$80.00
Your Price
$80.00
Cayman Ro 41-0960 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-29621-10
MFG.PART:
29621-10
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Ro 41-0960 is a catechol-O-methyltransferase (COMT) inhibitor. It prevents dopaminergic neuron loss induced by L-DOPA (Item No. ) in primary rat rostral mesencephalic tegmentum cultures (EC50 = 0.1 µM). Ro 41-0960 (30 mg/kg) potentiates L-DOPA and carbidopa-induced reversal of reserpine-induced akinesias in rats and reserpine-induced catalepsy and hypothermia in mice. It reduces striatal 3-methyl-DOPA levels and increases striatal dopamine (Item No. ) and 3,4-dihydroxyphenylacetic acid (DOPAC; Item No. ) levels in rats. Ro 41-0960 (150 mg/kg) also reduces fibroid volume in the Eker rat model of uterine fibroids.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(3,4-
CAS Number
125628-97-9
Molecular Formula
C13H8FNO5
Formula Weight
277.2
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 20 mg/mL
- DMSO: 20 mg/mL
- Ethanol: 20 mg/mL
- PBS (pH 7.2): 0.2 mg/mL
λmax
219, 258, 278 nm
SMILES
OC1=C(O)C=C(C(C2=CC=CC=C2F)=O)C=C1[N+]([O-])=O
InChi Code
InChI=1S/C13H8FNO5/c14-9-4-2-1-3-8(9)12(17)7-5-10(15(19)20)13(18)11(16)6-7/h1-6,16,18H
InChi Key
RQPAUNZYTYHKHA-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-29621-10 |
|---|---|
| Supplier Part Number | 29621-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 125628-97-9 |
| Energy Star | No |
| Green | No |
| Controlled | N |