Cayman S-Acetyl-L-glutathione

S-Acetyl-L-glutathione is a derivative of glutathione (GSH; Item No. 10007461).¹ It is more stable in plasma than GSH and, unlike GSH, can be taken up into cells, where it is converted to GSH by intracellular thioesterases.^1,2,3 S-Acetyl-L-glutathione (50 μM) increases intracellular GSH levels in primary fibroblasts derived from patients with glutathione synthetase deficiency.¹ It induces apoptosis in Daudi, Raji, and Jurkat lymphoma cells when used at a concentration of 5 mm.⁴ It inhibits the replication of herpes simplex virus 1 (HSV-1) in human foreskin fibroblasts when used at concentrations of 5 and 10 mm.² S-Acetyl-L-glutathione (6.25 μg/g per day), but not GSH, increases survival in a mouse model of HSV-1 infection.

WARNING This product is not for human or veterinary use.