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Cayman GLP-1R Agonist DMB
List Price
$223.00
Your Price
$223.00
Cayman GLP-1R Agonist DMB - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-29678-5
MFG.PART:
29678-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
GLP-1R agonist DMB is an agonist of glucagon-like peptide 1 receptor (GLP-1R; KB = 26.3 nM for the recombinant human receptor).1 It inhibits forskolin-induced cAMP accumulation in BHK cells expressing the recombinant human receptor with an EC50 value of 101 nM.2 GLP-1R (100 and 1,000 nM) increases insulin levels induced by D-(+)-glucose (Item No. 23733) in pancreatic islets isolated from wild-type, but not Glp1r knockout, mice. It reduces fasting plasma glucose levels in mice when administered at a dose of 5 µmol/kg.3
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
6,7-dichloro-
CAS Number
281209-71-0
Molecular Formula
C13H15Cl2N3O2S
Formula Weight
348.2
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMSO: soluble
λmax
223, 264 nm
SMILES
ClC1=C(Cl)C=C(N=C(NC(C)(C)C)C(S(C)(=O)=O)=N2)C2=C1
InChi Code
InChI=1S/C13H15Cl2N3O2S/c1-13(2,3)18-11-12(21(4,19)20)17-10-6-8(15)7(14)5-9(10)16-11/h5-6H,1-4H3,(H,16,18)
InChi Key
GNZCSGYHILBXLL-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-29678-5 |
|---|---|
| Supplier Part Number | 29678-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 281209-71-0 |
| Energy Star | No |
| Green | No |
| Controlled | N |