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Cayman Tolrestat
List Price
$32.00
Your Price
$32.00
Cayman Tolrestat - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-29693-1
MFG.PART:
29693-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Rp-8-bromo-Cyclic AMPS (Rp-8-bromo-cAMPS) is a cell-permeable cAMP analog that combines an exocyclic sulfur substitution in the equatorial position of the cyclophosphate ring with a bromine substitution in the adenine base of cAMP., It acts as an antagonist of cAMP-dependent protein kinases (PKAs) and is resistant to hydrolysis by cyclic nucleotide phosphodiesterases. Rp-8-bromo-cAMPS more effectively antagonizes cAMP-dependent activation of purified PKA type I from rabbit muscle than PKA type II from bovine heart.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
8-bromo-
CAS Number
925456-59-3
Synonyms
- 8-Bromo
adenosine 3,5-cyclic monophosphoro thioate, Rp-isomer - Rp-8-Br-
cAMPS - Rp-8-bromo-
cAMPS
Molecular Formula
C10H10BrN5O5PS • Na
Formula Weight
446.2
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/ml
- DMSO: 25 mg/ml
- Ethanol: 0.5 mg/ml
- PBS (pH 7.2): 10 mg/ml
λmax
212, 263 nm
SMILES
O[C@H]1[C@H](N2C(Br)=NC3=C2N=CN=C3N)O[C@H]4[C@H]1O[P@@](OC4)([S-])=O.[Na+]
InChi Code
InChI=1S/C10H11BrN5O5PS.Na/c11-10-15-4-7(12)13-2-14-8(4)16(10)9-5(17)6-3(20-9)1-19-22(18,23)21-6;/h2-3,5-6,9,17H,1H2,(H,18,23)(H2,12,13,14);/q;+1/p-1/t3-,5-,6-,9-,22-;/m1./s1
InChi Key
SKJLJCVVXRNYGJ-FBGJTXKBSA-M
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-29693-1 |
|---|---|
| Featured | No |
| Supplier Part Number | 29693-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | Canada |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 82964-04-3 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |