We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn about our cookie policy.
Cayman MT-DADMe-ImmA
List Price $332.00 Your Price $332.00
Cayman MT-DADMe-ImmA - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-29711-10
MFG.PART: 29711-10
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
MT-DADMe-ImmA is an inhibitor of 5-methylthioadenosine phosphorylase (MTAP; Ki = 1.7 nM).1 It increases levels of MTA (Item No. 15593), a product of polyamine metabolism, in FaDu human squamous cell carcinoma cells when used at a concentration of 1 µM.2 MT-DADMe-ImmA (5, 9, and 21 mg/kg per day for 28 days) reduces tumor growth in a FaDu mouse xenograft model.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(3R,4S)-1-
CAS Number
653592-04-2
Synonyms
- Methylthio-DADMe-Immucillin A
- MTDIA
Molecular Formula
C13H19N5OS
Formula Weight
293.4
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 10 mg/mL
- DMSO: 10 mg/mL
- PBS (pH 7.2): 1 mg/mL
λmax
231, 279 nm
SMILES
NC1=C2C(C(CN3C[C@H](O)[C@@H](CSC)C3)=CN2)=NC=N1
InChi Code
InChI=1S/C13H19N5OS/c1-20-6-9-4-18(5-10(9)19)3-8-2-15-12-11(8)16-7-17-13(12)14/h2,7,9-10,15,19H,3-6H2,1H3,(H2,14,16,17)/t9-,10+/m1/s1
InChi Key
NTHMDFGHOCNNOE-ZJUUUORDSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-29711-10 |
|---|---|
| Supplier Part Number | 29711-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 653592-04-2 |
| Energy Star | No |
| Green | No |
| Controlled | N |