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Cayman RJR 2429 (hydrochloride)
List Price $472.00 Your Price $472.00
Cayman RJR 2429 (hydrochloride) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-29745-25
MFG.PART: 29745-25
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
RJR 2429 is a nicotinic acetylcholine receptor (AChR) agonist.1 It is selective for α4β2 or α7 subunit-containing nicotinic AChRs (Kis = 0.7 and 10.9 nM in isolated rat cortex and isolated rat hippocampus, respectively) over α1βɣδ subunit-containing nicotinic AChRs (EC50 = 1,000 nM in PC12 cells). RJR 2429 induces dopamine release from isolated rat striatal synaptosomes (EC50 = 2.4 nM) and increases nicotine-induced elevations in epinephrine and norepinephrine levels in isolated rat adrenal gland when used at a concentration of 100 µM.2,3 It inhibits nicotine-induced ion flux in isolated rat thalamic synaptosomes (IC50 = 154 nM).2
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2-(3-pyridi
CAS Number
1021418-53-0
Molecular Formula
C12H16N2 • 2HCl
Formula Weight
261.2
Purity
≥98%
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- DMSO: 100 mm
- Water: 100 mm
SMILES
C12CCN(CC2)C(C3=CN=CC=C3)C1.Cl.Cl
InChi Code
InChI=1S/C12H16N2.2ClH/c1-2-11(9-13-5-1)12-8-10-3-6-14(12)7-4-10;;/h1-2,5,9-10,12H,3-4,6-8H2;2*1H
InChi Key
PIUNXHHZRIUBOV-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-29745-25 |
|---|---|
| Supplier Part Number | 29745-25 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1021418-53-0 |
| Energy Star | No |
| Green | No |
| Controlled | N |