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Cayman PKG Drug G1
List Price $268.00 Your Price $268.00
Cayman PKG Drug G1 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-29768-50
MFG.PART: 29768-50
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
PKG drug G1 is an activator of protein kinase GIα (PKGIα).1 It induces relaxation in U-46619-precontracted mesenteric arteries isolated from wild-type, but not oxidation-insensitive Cys42Ser PKGIα knock-in, mice in a concentration-dependent manner. PKG drug G1 (14.8 mg/kg) induces oxidation of PKGIα, a marker of activation, in the aorta in a mouse model of angiotensin II-induced hypertension. It decreases mean arterial pressure in the same model when administered at a dose of 20 mg/kg per day for four days.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
5-[(2-methyl-
CAS Number
374703-78-3
Molecular Formula
C13H11N3OS
Formula Weight
257.3
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 25 mg/mL
- DMSO: 20 mg/mL
- Ethanol: 2 mg/mL
- PBS (pH 7.2): Partially soluble
λmax
228, 286, 415 nm
SMILES
CC1=C(/C=C2C(NC(N/2)=S)=O)C3=CC=CC=C3N1
InChi Code
InChI=1S/C13H11N3OS/c1-7-9(6-11-12(17)16-13(18)15-11)8-4-2-3-5-10(8)14-7/h2-6,14H,1H3,(H2,15,16,17,18)/b11-6-
InChi Key
SNLLEQAPNVMOOT-WDZFZDKYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-29768-50 |
|---|---|
| Supplier Part Number | 29768-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 374703-78-3 |
| Energy Star | No |
| Green | No |
| Controlled | N |