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Cayman ACTB-1003
List Price
$54.00
Your Price
$54.00
Cayman ACTB-1003 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-30069-1
MFG.PART:
30069-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
ACTB-1003 is a multi-kinase inhibitor (IC50s = 6, 2, 4, 5, and 32 nM for FGFR1, VEGFR2, Tie-2, RSK, and p70S6K, respectively). It inhibits growth of OPM2 human multiple myeloma and murine Ba/F3-TEL-FGFR1 leukemia cells in vitro. ACTB-1003 inhibits tumor angiogenesis in an H460 mouse xenograft model. It also reduces tumor growth in an HCT116 mouse xenograft model when administered in combination with 5-fluorouracil (5-FU; Item No. ) or paclitaxel (Item No. ).
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-[4-[4-amino-
CAS Number
939805-30-8
Molecular Formula
C27H26F5N7O3
Formula Weight
591.5
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/mL
- DMSO: 30 mg/mL
- DMSO:PBS (pH 7.2) (1:2): 0.33 mg/mL
- Ethanol: 1 mg/mL
SMILES
NC1=NC=NN2C1=C(C3=CC(F)=C(NC(NC4=CC(C(F)(F)F)=CC=C4F)=O)C=C3)C(COC)=C2CN5CCOCC5
InChi Code
InChI=1S/C27H26F5N7O3/c1-41-13-17-22(12-38-6-8-42-9-7-38)39-24(25(33)34-14-35-39)23(17)15-2-5-20(19(29)10-15)36-26(40)37-21-11-16(27(30,31)32)3-4-18(21)28/h2-5,10-11,14H,6-9,12-13H2,1H3,(H2,33,34,35)(H2,36,37,40)
InChi Key
GZPJCJKUZPUFAL-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-30069-1 |
|---|---|
| Supplier Part Number | 30069-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 939805-30-8 |
| Energy Star | No |
| Green | No |
| Controlled | N |