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Cayman Glipizide-d11
List Price
$169.00
Your Price
$169.00
Cayman Glipizide-d11 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-30074-500
MFG.PART:
30074-500
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Glipizide-d11 is intended for use as an internal standard for the quantification of glipizide (Item No. ) by GC- or LC-MS. Glipizide is a hypoglycemic agent. It inhibits ATP-sensitive potassium (KATP) channels in primary mouse pancreatic β cells (IC50 = 6.4 nM). Glipizide induces insulin release from isolated rat pancreatic tissue with an EC50 value of 40 nM. Dietary administration of glipizide (5 mg/kg per day for 10 days) increases the number of insulin receptors on isolated and purified mouse liver plasma membranes. It reduces plasma glucose and triglyceride, but not total cholesterol, levels and increases plasma insulin levels in a rat model of diabetes induced by a high-fat diet and streptozotocin (STZ; Item No. ) when administered orally at a dose of 5 mg/kg. Formulations containing glipizide have been used in the treatment of type 2 diabetes.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-[2-[4-[[[(
CAS Number
1189426-07-0
Synonyms
- CP 28720
- K 4024
- TK 1320
Molecular Formula
C21H16D11N5O4S
Formula Weight
456.6
Purity
≥98% deuterated forms (d1-d11)
Formulation
A solid
Solubility
- DMSO: Slightly soluble
- Ethyl Acetate: Slightly soluble
SMILES
CC1=CN=C(C(NCCC2=CC=C(S(NC(NC3([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C3([2H])[2H])=O)(=O)=O)C=C2)=O)C=N1
InChi Code
InChI=1S/C21H27N5O4S/c1-15-13-24-19(14-23-15)20(27)22-12-11-16-7-9-18(10-8-16)31(29,30)26-21(28)25-17-5-3-2-4-6-17/h7-10,13-14,17H,2-6,11-12H2,1H3,(H,22,27)(H2,25,26,28)/i2D2,3D2,4D2,5D2,6D2,17D
InChi Key
ZJJXGWJIGJFDTL-KVEFGMAKSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-30074-500 |
|---|---|
| Supplier Part Number | 30074-500 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | Canada |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1189426-07-0 |
| Energy Star | No |
| Green | No |
| Controlled | N |