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Cayman Radezolid
List Price $36.00 Your Price $36.00
Cayman Radezolid - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-30092-1
MFG.PART: 30092-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Radezolid is an oxazolidinone antibiotic and a derivative of linezolid (Item No. ). It is active against a variety of bacterial clinical isolates, including strains of methicillin-sensitive and -resistant S. aureus, vancomycin-sensitive and -resistant E. faecalis and E. faecium, and linezolid-resistant S. aureus, S. epidermidis, E. faecalis, E. faecium, and S. pneumoniae (MICs = ≤0.25-64 µg/mL). Radezolid is also active against L. monocytogenes, S. aureus, L. pneumophila, and S. epidermidis in THP-1 macrophages (EC50s = 0.62, 0.63, 8.45, and 2.99 mg/L, respectively). It inhibits protein translation in isolated wild-type and linezolid-resistant S. aureus 70S ribosomes but not rabbit reticulocyte lysates (IC50s = 0.02, 0.03, and >2 µM, respectively). Radezolid is efficacious in a mouse model of S. pneumoniae-induced peritonitis with a 50% protective dose (PD50) value of 1.3 mg/kg per day.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-[[(5S)-3-
CAS Number
869884-78-6
Synonyms
- Rx-01_667
- RX-1741
Molecular Formula
C22H23FN6O3
Formula Weight
438.5
Purity
≥95%
Formulation
A solid
Solubility
- DMF: 2mg/mL
- DMSO: 2mg/mL
- DMSO:PBS (pH 7.2) (1:3): 0.25mg/mL
SMILES
O=C1N(C2=CC=C(C3=CC=C(CNCC4=CN=NN4)C=C3)C(F)=C2)C[C@H](CNC(C)=O)O1
InChi Code
InChI=1S/C22H23FN6O3/c1-14(30)25-12-19-13-29(22(31)32-19)18-6-7-20(21(23)8-18)16-4-2-15(3-5-16)9-24-10-17-11-26-28-27-17/h2-8,11,19,24H,9-10,12-13H2,1H3,(H,25,30)(H,26,27,28)/t19-/m0/s1
InChi Key
BTTNOGHPGJANSW-IBGZPJMESA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-30092-1 |
|---|---|
| Supplier Part Number | 30092-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 869884-78-6 |
| Energy Star | No |
| Green | No |
| Controlled | N |